CALL FOR PAPERS MicroRNA and Tissue Injury MicroRNAs in skin and wound healing

نویسندگان

  • Jaideep Banerjee
  • Yuk Cheung Chan
  • Chandan K. Sen
چکیده

Banerjee J, Chan YC, Sen CK. MicroRNAs in skin and wound healing. Physiol Genomics 43: 543–556, 2011. First published October 19, 2010; doi:10.1152/physiolgenomics.00157.2010.—MicroRNAs (miRNAs) are small endogenous RNA molecules 22 nt in length. miRNAs are capable of posttranscriptional gene regulation by binding to their target messenger RNAs (mRNAs), leading to mRNA degradation or suppression of translation. miRNAs have recently been shown to play pivotal roles in skin development and are linked to various skin pathologies, cancer, and wound healing. This review focuses on the role of miRNAs in cutaneous biology, the various methods of miRNA modulation, and the therapeutic opportunities in treatment of skin diseases and wound healing.

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تاریخ انتشار 2011